Spinach and Artichoke Chicken Casserole
Creamy, cheesy, and packed with tender chicken, this casserole is a cozy hug in a baking dish.
Total: 60 minPrep: 15 minCook: 45 min6 servingsDifficulty: Easy⭐ 4.7 (123+ ratings)$
Ingredients
Servings:
- 1 1/2 cups uncooked penne pasta
- 1 pound boneless, skinless chicken breasts, cooked and cubed
- 1 10-ounce package frozen spinach, thawed and drained
- 1 14-ounce can artichoke hearts, drained and chopped
- 1 cup shredded mozzarella cheese
- 1/2 cup grated Parmesan cheese
- 1 cup sour cream
- 1 cup mayonnaise
- 1 teaspoon garlic powder
- 1 teaspoon dried oregano
- 1/2 teaspoon black pepper
- 1/2 teaspoon salt
- 1/4 teaspoon red pepper flakes (optional)
Steps
- 1 Preheat oven to 375°F.
- 2 Cook pasta according to package instructions; drain and set aside.
- 3 In a large bowl, combine cooked pasta, chicken, spinach, and artichokes.
- 4 In a separate bowl, mix sour cream, mayonnaise, garlic powder, oregano, black pepper, salt, and red pepper flakes if using.
- 5 Pour the sauce over the pasta mixture and stir until well combined.
- 6 Transfer mixture to a greased 9x13 inch baking dish.
- 7 Top with mozzarella and Parmesan cheeses.
- 8 Bake for 30-35 minutes, or until bubbly and cheese is melted and golden.
- 9 Let stand for 5 minutes before serving.
Equipment
- 9x13 inch baking dish
- Mixing bowls
- Oven
Variations
Substitutions
Pairings
- A crisp Chardonnay complements the rich flavors.
- Sparkling water with lemon for a refreshing drink.
Nutrition
Calories:
450 kcal
Fat:
25g fat
Carbs:
25g carbohydrates
Protein:
28g protein
Fiber:
3g fiber
Sugar:
3g sugar
Sodium:
700mg sodium
Tips
Storage
Store leftovers in an airtight container in the fridge for up to 3 days. Reheat in a 350°F oven until warmed through.
Freezing: Freezes well for up to 2 months. Thaw overnight in the fridge and bake covered at 350°F for 45 minutes, then uncover and bake an additional 10-15 minutes.
Serving Suggestions
FAQ
Can I make this casserole ahead of time?
Absolutely! Prepare it up to the baking step, cover, and refrigerate for up to a day.
What can I use instead of mayonnaise?
Greek yogurt works well as a substitute for a healthier option.