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Baked pasta with alfredo sauce, chicken, and melted cheese in a rectangular baking dish.

Alfredo Chicken Penne Bake

Creamy, cheesy alfredo sauce envelops tender chicken and penne in a bubbly, golden-brown casserole that'll make your taste buds do a happy dance.

Total: 55 minPrep: 15 minCook: 40 min6 servingsDifficulty: Easy⭐ 4.7 (123+ ratings)$

Ingredients

Servings:

Steps

  1. 1 Preheat oven to 375°F.
  2. 2 Cook penne according to package instructions until al dente; drain.
  3. 3 In a large bowl, mix heavy cream, 1 1/2 cups mozzarella, Parmesan, garlic, basil, oregano, salt, and pepper.
  4. 4 Stir in cooked penne and chicken until well combined.
  5. 5 Transfer mixture to a greased 9x13 inch baking dish.
  6. 6 Optional: Mix breadcrumbs with melted butter and sprinkle over the top.
  7. 7 Bake uncovered for 30-35 minutes, or until bubbly and golden.
  8. 8 Sprinkle remaining 1/2 cup mozzarella over the top and bake for another 5 minutes until melted.
  9. 9 Let stand for 5 minutes before serving.

Equipment

Variations

Substitutions

Pairings

Nutrition

Calories: 650 kcal
Fat: 35g fat
Carbs: 45g carbohydrates
Protein: 30g protein
Fiber: 2g fiber
Sugar: 5g sugar
Sodium: 800mg sodium

Tips

Storage

Store leftovers in an airtight container in the refrigerator for up to 3 days. Reheat in the oven at 350°F until heated through.

Freezing: Freezes well for up to 2 months. Thaw overnight in the refrigerator and bake covered at 350°F for 30 minutes, then uncover and bake another 10-15 minutes.

Serving Suggestions

FAQ

Can I use rotisserie chicken?

Absolutely! It's a quick and flavorful option.

How do I make this vegan?

Use vegan alfredo sauce and substitute chicken with tofu or hearty vegetables.

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